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- A drama centered on the personal and professional lives of five surgical interns and their supervisors.
- Starting over isn't easy, especially for John Nolan who, after a life-altering incident, is pursuing his dream of joining the LAPD. As their oldest rookie, he's met with skepticism from those who see him as just a walking midlife crisis.
- This series follows the Special Victims Unit, a specially trained squad of detectives in the New York City Police Department that investigate sexually related crimes.
- New Jersey mob boss Tony Soprano deals with personal and professional issues in his home and business life that affect his mental state, leading him to seek professional psychiatric counseling.
- The series follows Adrian Monk, a brilliant former San Francisco detective, who now consults the police as a private consultant whilst battling with an obsessive-compulsive disorder.
- Using a crack team of doctors and his wits, an antisocial maverick doctor specializing in diagnostic medicine does whatever it takes to solve puzzling cases that come his way.
- Two brothers follow their father's footsteps as hunters, fighting evil supernatural beings of many kinds, including monsters, demons, and gods that roam the earth.
- The survivors of a plane crash are forced to work together in order to survive on a seemingly deserted tropical island.
- Four female New Yorkers gossip about their sex lives (or lack thereof) and find new ways to deal with being a woman in the late 1990s.
- In a wacky Rhode Island town, a dysfunctional family strives to cope with everyday life as they are thrown from one crazy scenario to another.
- New York's finest police detectives and prosecutors fight to make the city a safer place. With integrity as the guiding force from investigation to verdict, the teams weigh every perspective in their commitment to finding justice.
- A young convict joins a firefighting program looking for redemption and a shortened prison sentence. He and other inmates work alongside elite firefighters to extinguish massive blazes across the region.
- The lives, loves, dangers and disasters in the town, Mystic Falls, Virginia. Creatures of unspeakable horror lurk beneath this town as a teenage girl is suddenly torn between two vampire brothers.
- A skeptical clinical psychologist joins a priest-in-training and a blue collar contractor as they investigate supposed abnormal events, including, demonic possession, and other extraordinary occurrences to see if there's a scientific explanation or if something truly supernatural's at work.
- The doctors who work in the ER at the County General Hospital in Chicago grapple with ups and downs in their personal and professional lives while trying to give apt medical care to their patients.
- When a psychopath commits murders based on novelist Castle's books, Detective Beckett seeks his help to solve the case. He decides to work with her and uses his experiences as research for his novels.
- Three girls are kidnapped by a man with a diagnosed 23 distinct personalities. They must try to escape before the apparent emergence of a frightful new 24th.
- Privileged teens living on the Upper East Side of New York can hide no secret from the ruthless blogger who is always watching.
- Follows the misadventures of four irreverent grade-schoolers in the quiet, dysfunctional town of South Park, Colorado.
- This spinoff of the critically acclaimed show Grey's Anatomy follows the lives of the men and women of firehouse station 19 in Seattle, Washington.
- A dramedy centering around the relationship between a thirtysomething single mother and her teen daughter living in Stars Hollow, Connecticut.
- A young Clark Kent struggles to find his place in the world as he learns to harness his alien powers for good and deals with the typical troubles of teenage life in Smallville, Kansas.
- A young woman with a troubled past is drawn to a small town in Maine where fairy tales are to be believed.
- An ex-CIA agent and a wealthy programmer save lives via a surveillance AI that sends them the identities of civilians involved in impending crimes. However, the details of the crimes, including the civilians' roles, are left a mystery.
- An insomniac office worker and a devil-may-care soap maker form an underground fight club that evolves into much more.
- Half-brothers Lucas and Nathan Scott trade between kinship and rivalry both on the basketball court and in the hearts of their friends in the small, but not so quiet town of Tree Hill, North Carolina.
- A woman is kidnapped by a stranger on a routine flight. Threatened by the potential murder of her father, she is pulled into a plot to assist her captor in a political assassination.
- Cady Heron is a hit with The Plastics, the A-list girl clique at her new school, until she makes the mistake of falling for Aaron Samuels, the ex-boyfriend of alpha Plastic Regina George.
- Alicia Florrick has been a good wife to her husband, a former state's attorney. After a very humiliating sex and corruption scandal, he is behind bars. She must now provide for her family and returns to work as a litigator in a law firm.
- Secrets and truths unfold through the lives of female friends in one suburban neighborhood after the mysterious suicide of a neighbor.
- A young programmer is selected to participate in a ground-breaking experiment in synthetic intelligence by evaluating the human qualities of a highly advanced humanoid A.I.
- Two affluent suburban girls clash with the Latino gang culture of East Los Angeles.
- Literature student Anastasia Steele's life changes forever when she meets handsome, yet tormented, billionaire Christian Grey.
- When a commercial airliner suddenly reappears after being missing for five years, those aboard must reintegrate into society.
- A young F.B.I. cadet must receive the help of an incarcerated and manipulative cannibal killer to help catch another serial killer, a madman who skins his victims.
- An F.B.I. agent is forced to work with an institutionalized scientist and his son in order to rationalize a brewing storm of unexplained phenomena.
- Thomas is deposited in a community of boys after his memory is erased, soon learning they're all trapped in a maze that will require him to join forces with fellow "runners" for a shot at escape.
- A wealthy New York City investment banking executive, Patrick Bateman, hides his alternate psychopathic ego from his co-workers and friends as he delves deeper into his violent, hedonistic fantasies.
- When Bella Swan moves to a small town in the Pacific Northwest, she falls in love with Edward Cullen, a mysterious classmate who reveals himself to be a 108-year-old vampire.
- A young African-American visits his white girlfriend's parents for the weekend, where his simmering uneasiness about their reception of him eventually reaches a boiling point.
- An astronaut becomes stranded on Mars after his team assume him dead, and must rely on his ingenuity to find a way to signal to Earth that he is alive and can survive until a potential rescue.
- When Jacob (Asa Butterfield) discovers clues to a mystery that stretches across time, he finds Miss Peregrine's Home for Peculiar Children. But the danger deepens after he gets to know the residents and learns about their special powers.
- Three Halliwell sisters discover that they are descendants of a line of good female witches and are destined to fight against the forces of evil, using their combined power of witchcraft known as the "Power of Three".
- A Manhattan doctor embarks on a bizarre, night-long odyssey after his wife's admission of unfulfilled longing.
- In Jumanji: The Next Level, the gang is back but the game has changed. As they return to rescue one of their own, the players will have to brave parts unknown from arid deserts to snowy mountains, to escape the world's most dangerous game.
- NCIS's covert operations team go undercover to investigate cases involving terrorism and National Security.
- An idealistic FBI agent is enlisted by a government task force to aid in the escalating war against drugs at the border area between the U.S. and Mexico.
- A crime-solving duo that cracks the NYPD's most impossible cases. Following his fall from grace in London, eccentric Sherlock escapes to New York where his father forces him to live with his worst nightmare - a sober companion, Dr. Watson.
- Philip J. Fry, a pizza delivery boy, is accidentally frozen in 1999 and thawed out on New Year's Eve 2999.
- Four teenagers are sucked into a magical video game, and the only way they can escape is to work together to finish the game.