After a wealthy San Francisco banker is given an opportunity to participate in a mysterious game, his life is turned upside down as he begins to question if it might really be a concealed conspiracy to destroy him.
Stranded at a desolate Nevada motel during a nasty rain storm, ten strangers become acquainted with each other when they realize that they're being killed off one by one.
Three years ago, entomologist Dr. Susan Tyler genetically created an insect to kill cockroaches carrying a virulent disease. Now, the insects are out to destroy their only predator, mankind.