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- CreatorChuck LorreBill PradyStarsJohnny GaleckiJim ParsonsKaley CuocoA woman who moves into an apartment across the hall from two brilliant but socially awkward physicists shows them how little they know about life outside of the laboratory.
- CreatorDaniel ChunStarsJohn StamosPaget BrewsterJosh PeckA confirmed bachelor discovers he's a dad--and a grandfather.
- CreatorGemma BakerEddie GorodetskyChuck LorreStarsAllison JanneyAnna FarisMimi KennedyA newly sober single mom tries to pull her life together in Napa Valley while dealing with her wayward mother.
- CreatorSteven LevitanChristopher LloydStarsEd O'NeillSofía VergaraJulie BowenThree different, but related, families face trials and tribulations in their own uniquely comedic ways.
- CreatorWhitney CummingsMichael Patrick KingStarsKat DenningsBeth BehrsGarrett MorrisTwo young women waitressing at a greasy spoon diner strike up an unlikely friendship in the hopes of launching a successful business - if only they can raise the cash.
- CreatorMike BarkerSeth MacFarlaneMatt WeitzmanStarsSeth MacFarlaneWendy SchaalScott GrimesThe escapades of Stan Smith, a conservative C.I.A. Agent dealing with family life, and keeping America safe.
- CreatorTad QuillStarsJane LynchMaggie LawsonKyle BornheimerAllison isn't quite sure if her new friend, Amy, is her guardian angel or a crazy person.
- CreatorDan BerendsenStarsJean-Luc BilodeauDerek ThelerMelissa PetermanA 20-something bachelor bartender becomes an unlikely parent when an ex-girlfriend leaves a baby girl on his doorstep.
- CreatorLouis C.K.Zach GalifianakisJonathan KriselStarsZach GalifianakisMartha KellyLouie AndersonAfter failing at a prestigious French clowning college, Chip Baskets looks to keep his dream of becoming a professional clown alive.
- CreatorLoren BouchardJim DauteriveStarsH. Jon BenjaminDan MintzEugene MirmanBob Belcher runs a struggling burger shop with his wife and three children.
- CreatorVince GilliganStarsBryan CranstonAaron PaulAnna GunnA chemistry teacher diagnosed with inoperable lung cancer turns to manufacturing and selling methamphetamine with a former student in order to secure his family's future.
- CreatorRachel BloomAline Brosh McKennaStarsRachel BloomDonna Lynne ChamplinVincent Rodriguez IIIA young woman abandons a choice job at a law firm and her life in New York in an attempt to find happiness in the unlikely locale of West Covina, California.
- CreatorJohn FoxKen JeongJared SternStarsKen JeongSuzy NakamuraTisha CampbellA frustrated doctor juggles his career, marriage, and family.
- CreatorSeth MacFarlaneDavid ZuckermanStarsAlex BorsteinSeth MacFarlaneSeth GreenIn a wacky Rhode Island town, a dysfunctional family strives to cope with everyday life as they are thrown from one crazy scenario to another.
- CreatorNahnatchka KhanStarsRandall ParkConstance WuHudson YangA Taiwanese family makes their way in America during the 1990s.
- CreatorJennie Snyder UrmanStarsGina RodriguezAndrea NavedoYael GrobglasA young, devout Catholic woman discovers that she was accidentally artificially inseminated.
- CreatorTom KapinosStarsTom EllisLauren GermanKevin AlejandroLucifer Morningstar has decided he's had enough of being the dutiful servant in Hell and decides to spend some time on Earth to better understand humanity. He settles in Los Angeles - the City of Angels.
- CreatorDan LevyEugene LevyStarsEugene LevyCatherine O'HaraDan LevyAfter being a victim of fraud, Johnny Rose and his family go from extremely wealthy to penniless overnight. The only asset left to them is a small, unsophisticated town: Schitt's Creek. They relocate there. Culture shock ensues.
- CreatorErin CardilloRichard KeithStarsJosh ZuckermanNathaniel BuzolicKrista AllenBudding Portland restaurateur Nate's world is turned upside down when he finds out his best friend/roommate is now dating his recently separated mother.
- CreatorTrey ParkerMatt StoneBrian GradenStarsTrey ParkerMatt StoneIsaac HayesFollows the misadventures of four irreverent grade-schoolers in the quiet, dysfunctional town of South Park, Colorado.
- CreatorWill ForteStarsWill ForteJanuary JonesCleopatra ColemanAlmost two years after a virus wiped out most of the human race, Phil Miller only wishes for some company, but soon gets more than he bargained for when that company shows up in the form of other survivors.
- CreatorDanny JacobsonJoe KeenanMatthew PerryStarsMatthew PerryThomas LennonLindsay SloaneAfter being kicked out of their houses by their wives, two friends try to share an apartment, but their ideas of housekeeping and lifestyles are as different as night and day.
- CreatorJames L. BrooksMatt GroeningSam SimonStarsDan CastellanetaNancy CartwrightHarry ShearerThe satiric half-hour adventures of a working-class family in the misfit city of Springfield.
- CreatorDJ NashStarsMark-Paul GosselaarTone BellVanessa LacheyA look at the life of two best friends, a meek politically correct Caucasian ethics professor and an easy-going African American, and their families.
- CreatorDavid HoldenStarsEmily OsmentJonathan SadowskiAimee CarreroA well-off young tech entrepreneur hires a feisty young food blogger to be his personal chef.