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- CreatorBill LawrenceStarsZach BraffDonald FaisonSarah ChalkeIn the unreal world of Sacred Heart Hospital, intern John "J.D." Dorian learns the ways of medicine, friendship and life.
- CreatorDan HarmonStarsJoel McHaleDanny PudiDonald GloverA suspended lawyer is forced to enroll in a community college with an eccentric staff and student body.
- CreatorJulie PlecKevin WilliamsonStarsNina DobrevPaul WesleyIan SomerhalderThe lives, loves, dangers and disasters in the town, Mystic Falls, Virginia. Creatures of unspeakable horror lurk beneath this town as a teenage girl is suddenly torn between two vampire brothers.
- CreatorCarter BaysCraig ThomasStarsJosh RadnorJason SegelCobie SmuldersA father recounts to his children - through a series of flashbacks - the journey he and his four best friends took leading up to him meeting their mother.
- CreatorChuck LorreBill PradyStarsJohnny GaleckiJim ParsonsKaley CuocoA woman who moves into an apartment across the hall from two brilliant but socially awkward physicists shows them how little they know about life outside of the laboratory.
- CreatorEric KripkeStarsJared PadaleckiJensen AcklesJim BeaverTwo brothers follow their father's footsteps as hunters, fighting evil supernatural beings of many kinds, including monsters, demons, and gods that roam the earth.
- CreatorJeremy CarverAnna FrickeStarsSam WitwerMeaghan RathSam HuntingtonThree twenty-somethings share a house and try to live a normal life despite being a ghost, a werewolf, and a vampire.
- CreatorFrank DarabontStarsAndrew LincolnNorman ReedusMelissa McBrideSheriff Deputy Rick Grimes wakes up from a coma to learn the world is in ruins and must lead a group of survivors to stay alive.
- CreatorI. Marlene KingStarsTroian BellisarioAshley BensonLucy HaleFour friends band together against an anonymous foe who threatens to reveal their darkest secrets, while also investigating the disappearance of their best friend.
- CreatorBruno HellerStarsSimon BakerRobin TunneyTim KangA famous "psychic" outs himself as a fake, and starts working as a consultant for the California Bureau of Investigation so he can find "Red John", the madman who killed his wife and daughter.
- CreatorAlan BallStarsAnna PaquinStephen MoyerSam TrammellTelepathic waitress Sookie Stackhouse encounters a strange new supernatural world when she meets the mysterious Bill Compton, a southern Louisiana gentleman and vampire.
- CreatorDavid BenioffD.B. WeissStarsEmilia ClarkePeter DinklageKit HaringtonNine noble families fight for control over the lands of Westeros, while an ancient enemy returns after being dormant for millennia.
- CreatorStephen CarpenterDavid GreenwaltJim KoufStarsDavid GiuntoliRussell HornsbySilas Weir MitchellA homicide detective discovers he is a descendant of hunters who fight supernatural forces.
- CreatorJohnny CappsJulian JonesJake MichieStarsJohn HurtColin MorganBradley JamesThese are the brand new adventures of Merlin, the legendary sorcerer as a young man, when he was just a servant to young Prince Arthur on the royal court of Camelot, who has soon become his best friend, and turned Arthur into a great king and a legend.
- CreatorJoss WhedonStarsEliza DushkuHarry LennixFran KranzA top secret organization erases the identities of attractive young people, turning them into blank "dolls" ready for imprints of temporary identities they need to fulfill assignments for clients.
- CreatorAlfred GoughMiles MillarStarsTom WellingMichael RosenbaumAllison MackA young Clark Kent struggles to find his place in the world as he learns to harness his alien powers for good and deals with the typical troubles of teenage life in Smallville, Kansas.
- CreatorJoss WhedonStarsSarah Michelle GellarNicholas BrendonAlyson HanniganA young woman, destined to slay vampires, demons and other infernal creatures, deals with her life fighting evil, with the help of her friends.
- CreatorDavid GreenwaltJoss WhedonStarsDavid BoreanazCharisma CarpenterAlexis DenisofThe vampire Angel, cursed with a soul, moves to Los Angeles and aids people with supernatural-related problems while questing for his own redemption.
- CreatorConstance M. BurgeStarsHolly Marie CombsAlyssa MilanoBrian KrauseThree Halliwell sisters discover that they are descendants of a line of good female witches and are destined to fight against the forces of evil, using their combined power of witchcraft known as the "Power of Three".
- CreatorJosh SchwartzStarsMischa BartonAdam BrodyPeter GallagherA troubled youth becomes embroiled in the lives of a close-knit group of people in the wealthy, upper-class neighborhood of Newport Beach, Orange County, California.
- CreatorDarren StarJeff JudahGabe SachsStarsShenae Grimes-BeechTristan Mack WildsAnnaLynne McCordA Kansas family relocates to Beverly Hills, where their two children adapt to the infamous social drama of West Beverly Hills High.
- CreatorAdam HorowitzEdward KitsisStarsGinnifer GoodwinJennifer MorrisonLana ParrillaA young woman with a troubled past is drawn to a small town in Maine where fairy tales are to be believed.
- CreatorJames Manos Jr.StarsMichael C. HallJennifer CarpenterDavid ZayasHe's smart. He's lovable. He's Dexter Morgan, America's favorite serial killer, who spends his days solving crimes and nights committing them.
- CreatorLauren IungerichStarsAshley RickardsBeau MirchoffJillian Rose ReedAn unpopular 15-year-old gains immediate, yet unwanted, popularity at her high school when the student body mistakes an accident she has for a suicide attempt.
- CreatorWhitney CummingsMichael Patrick KingStarsKat DenningsBeth BehrsGarrett MorrisTwo young women waitressing at a greasy spoon diner strike up an unlikely friendship in the hopes of launching a successful business - if only they can raise the cash.