After learning that her friends, as well as herself, are the magical Elements of Harmony, studious unicorn Twilight Sparkle is sent by her mentor, Princess Celestia, to Ponyville to study the magic of friendship with help from her friends.
A young girl named Blythe Baxter moves to downtown city in an apartment above Littlest Pet Shop. She soon discovers she can understand animals. She goes on some crazy adventures with the pets.