- Lisa is a breast cancer survivor. She is an active spokesperson for breast cancer awareness.
- Lisa wrote the anthem for the National Suicide Prevention Campaign titled "Someone to Love Me for Me", a duet with Full Force (1987).
- Lisa has toured with David Bowie, Teena Marie, New Edition, Run-D.M.C., SWV, Salt-N-Pepa and Full Force.
- After her contract with Columbia Records was up (1993), Lisa Lisa left Lisa Lisa and made a run at a solo career with her album "LL77".
- Lisa's song "Head to Toe" hit #1 on the Billboard Hot 100 Chart in July 1987. Her second #1 "Lost in Emotion" peaked just two months later.
- Lisa had said that Nickelodeon's Taina (2001) was loosely based on her childhood. She played Taina's sharp-witted mother on the sitcom.
- Lisa sang background vocals on Patti LaBelle's song "I Got It Like That".
- She appeared with Stevie B., TKA, Sa-Fire and others at the eighth annual Forever Freestyle showcase at the Lehman College Center for the Performing Arts in the Bronx. (March 2014)
- She sang in her church choir, at the Church of the Sacred Heart of Jesus, along with her six sisters, and was an A student at Julia Richmond High School in Manhattan.
- Lisa was awarded "Most Successful Latin American Musician" by President George Bush (1990).
- Lisa recorded her first hit song at the age of 13, "I Wonder If I Take You Home".
- Lisa has sold over 20 million records. With over over 14 Top 40 hits.
- Lisa was the first Latino to cross over from the R&B to the Pop charts.
- Sister of Maria Velez. Aunt of Jose Soto.
- Lisa Lisa was offered the lead role of "Lisa" in the movie "Coming to America" by Eddie Murphy when he met her at a party.
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