- He played two seasons in the NFL with the Cincinnati Bengals (2008) and San Diego Chargers (2009), as well as on the practice squad with the Minnesota Vikings (2010-2011). He also played in the Arena Football League.
- Castille was a star football player at Alabama and went on to play in the NFL. His father, Jeremiah, and older brother, Tim, also played football in the NFL after attending Alabama. His younger brother Caleb also played at Alabama before starting his acting career.
- Simeon is the owner and Director of Athletics at Stille Academy in Pelham, AL.
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