New York, May 16 (Ians) A team of researchers at the US National Institutes of Health (Nih) has rolled out a clinical trial of an experimental mRNA-based universal influenza vaccine.
The Phase 1 trial will test the experimental vaccine, known as H1ssF-3928 mRNA-lnp, for safety and its ability to induce an immune response.
The vaccine uses a specific portion of a flu protein, hemagglutinin (Ha), to induce a broad immune response against influenza. While one portion of the Ha protein, known as the head, tends to change as the flu virus spreads and evolves, a more stable portion, known as the stem, evolves very slowly and is very similar across many different types of the flu virus.
By using the Ha stem as the basis for a vaccine, researchers hope to induce long-term immunity against a broad range of flu viruses. Unlike the earlier vaccine, the H1ssF-3928 mRNA-lnp vaccine candidate...
The Phase 1 trial will test the experimental vaccine, known as H1ssF-3928 mRNA-lnp, for safety and its ability to induce an immune response.
The vaccine uses a specific portion of a flu protein, hemagglutinin (Ha), to induce a broad immune response against influenza. While one portion of the Ha protein, known as the head, tends to change as the flu virus spreads and evolves, a more stable portion, known as the stem, evolves very slowly and is very similar across many different types of the flu virus.
By using the Ha stem as the basis for a vaccine, researchers hope to induce long-term immunity against a broad range of flu viruses. Unlike the earlier vaccine, the H1ssF-3928 mRNA-lnp vaccine candidate...
- 5/16/2023
- by Agency News Desk
- GlamSham
They were two of the most famous women in the world — Jacqueline Kennedy Onassis and her sister Lee Radziwill — and their lives have been written about countless times, but a new book, Jackie, Janet and Lee by J. Randy Taraborrelli, reveals new details about the sisters’ complicated relationship, their lifelong rivalry and the powerful influence of their mother, Janet Auchincloss.
Unlike previous Jackie biographers, Taraborrelli decided to focus on Jackie’s family, not John F. Kennedy’s famous clan.
“Jackie had a full life before she married J.F.K.,” Taraborrelli tells People in the latest issue, on newsstands Friday.
Unlike previous Jackie biographers, Taraborrelli decided to focus on Jackie’s family, not John F. Kennedy’s famous clan.
“Jackie had a full life before she married J.F.K.,” Taraborrelli tells People in the latest issue, on newsstands Friday.
- 1/24/2018
- by Liz McNeil
- PEOPLE.com
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