- He began his soccer career at the age of 18.
- Midfielder for C.A. Huracán (1999-2002), River Plate (2002-2005, 2015-16), F.C. Porto (Portugal, 2005-2009, 2012-2014), Olympique de Marseille (France, 2009-2011), Al Rayyan (Qatar, 2014-15) and Club Athletico Paranaense (Brazil, 2016-2021).
- Won the Pre-Olympic Tournament (2004) with Argentina U23.
- Honours with C.A. Huracán: Primera B Nacional x1 (2000). Honours with River Plate: Argentine Primera División x2 (2003 Clausura, 2004 Clausura); Copa Libertadores x1 (2015). Honours with F.C. Porto: Portuguese League x6 (2006, 2007, 2008, 2009, 2012, 2013); Portugal Cup x2 (2006, 2009); Portuguese Super Cup x2 (2012, 2013). Honours with Olympique de Marseille: French League x1 (2010); French League Cup x3 (2010, 2011, 2012); French Super Cup x2 (2010, 2011). Honours with Club Athletico Paranaense: Copa Sudamericana x1 (2018); J.League Cup x1 (2019); Brazil Cup x1 (2019).
- 45 appearances for Argentina National Football Team (2003-2011); scored 6 goals. Member of the Copa América 2004, 2007, and the Germany '06 squads.
- Father of, with 1st wife Pamela Cafure, Thomas González (b. 2004) and Román González (b. 2006).
- Member of the Argentina National team who finished runner-up of the Copa América in 2004 and 2007.
- Won the gold medal with Argentina Olympic Football Team in the 2004 Olympic Games.
- Won the Portuguese Golden Ball in 2009.
- Father of, with 2nd wife Andreia Marques, Mateo González (b. 2011).
- Reported by his 2nd wife Andreia Marques for domestic violence. (December 2017)
- His father is Uruguayan and his mother is Chilean.
- Captain of Club Athletico Paranaense from 2019-2021.
- Retired from football at the age 40. (May 2021)
- Played well over 200 games for F.C. Porto.
- Played well over 150 games for River Plate and Club Athletico Paranaense.
- Played well over 100 games for C.A. Huracán and Olympique de Marseille.
- Scored well over 100 goals in his career.
- Was assistant coach of Atlético Paranaense in 2021.
- Head coach of Ceará (Brazil, 2022).
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