Based on the files of the United States Department of Treasury, Commissioner Michael Barrows is an American Government Agent who is in Shanghai on narcotics business. While on board a police boat he notices a ship heading to Shanghai quickly. The Captain of the ship, the Kira Maru, panics and ruthlessly sends 100 Chinese slaves to a watery death. Barrows convinced that these deaths point to a huge drug smuggling operation heads to Shanghai. In Shanghai, while searching for the captain of the Kira Maru, he becomes suspicious of a women, Ann Grant, believing she is Jean Hawks the narcotics ring leader. He follows Grant and companion, Shu Pan through Cairo, Beirut, and Havana to catch Grant red handed.
—Kelly