The show is divided into two series, the first consisting of 36 episodes directed by Yoshio Takeuchi, and the second consisting of 37 episodes directed by Kenji Kodama. While the episodes of the first series are adapted from the manga, those of the second are completely original.
Cat's Eye, the bar managed by the three main sisters of the series, also appears in two other works by Tsukasa Hôjô, City Hunter (1987) and Angel Heart (2005), in which it is managed by Umibozu.
In the Italian comic book Nathan Never, the Frayn sisters (April, May, and July) are a reference to the sisters of Cat's Eye (1983).