Code 46 refers to the twenty-two chromosome pairs, plus the two sex chromosomes in human beings.
This movie takes place in 2050.
Mick Jones of The Clash sings the Clash song "Should I Stay Or Should I Go" in the karaoke-esque club scene, but he appears to get the words wrong. The song goes "If I go there will be trouble. If I stay it will be double", but he sings "If I go there will be trouble. If I go it will be double."
The dialogue is peppered with words from several different languages. This creates a feeling of a more amalgamated world.
In this "unified" world, you hear several languages mixed into English. "Papeles" is Spanish for "papers". "Claro" is Spanish for "Clear", "Sure, Okay". Other languages mixed in are French and Chinese.