Kris Aquino was supposed to play the role of the third wife, but preferred the role of the first wife. The producer initially wanted Dina Bonnevie to play the wicked role, but Lorna Tolentino, already in the cast, also wanted it. The producer selected Lorna after the actress vowed not to work in the project if the role was not given to her.
When Lorna Tolentino got the role of Belinda Que-Tan, the wicked wife, Dina Bonnevie was given the role of the good wife Lu-Shui. She refused, and the role went to Zsa Zsa Padilla, who won the Best Actress award in the Metro Manila Film Festival for her portrayal.
Christopher De Leon and Zoren Legaspi are also appeared in Paano Na? Sa Mundo Ni Janet (1994)
This is the third collaboration of Zoren Legaspi and Kris Aquino after Geron Olivar (1994) and The Fatima Buen Story (1994).
First Regal Films movie and the only film in the "Mano Po" franchise sponsored by Ginebra San Miguel Inc., through its Ginebra San Miguel product, the company was formerly known as La Tondeña Distillers, Inc. but however in February, the company was changed to its current name. In actual film, the GSMI plant in Cabuyao, Laguna as well as all GSM products are shown during both scenes.