Dave references the Prince of Monaco (pronouncing it mo-NOC-oh instead of MON-uh-co). At the time, the prince was Rainier III, who had married Grace Kelly a few years earlier. Interestingly, Rainier III outlived all of the cast members.
As smokers, Brian Keith and Joanna Moore both suffered with lung cancer. Moore would pass away from the disease. Keith committed suicide under the double stressors of the disease and losing his daughter to suicide.