First episode to include Robert David Hall as Dr. Al Robbins.
This is the first episode to feature the theme song 'Who Are You?' (coincidentally, the name of this episode), performed by The Who; CBS had trouble securing the rights to use the song, in time for the series first 5 episodes. From this episode onwards, though, the familiar song plays for every single title sequence.
First appearance of Pamela Gidley as forensic pathologist Teri Miller.
Episode title "Who Are You?" matches the theme song title "Who Are You?" by The Who.