Prue picks up a newspaper from the sidewalk with the headline "Firemen Doubt Fire was Accidental", the same newspaper prop used in Mrs. Doubtfire (1993), giving Robin Williams's character the idea for the name "Mrs. Doubtfire".
Actress Holly Marie Combs is the only actress left from the original casting that has appeared in every episode filmed. The original unaired Pilot was filmed with Lori Rom playing the part of Phoebe Halliwell.
The episode title is derived from Shakespeare's play Macbeth, in which the second of the three witches says, "By the pricking of my thumbs, Something wicked this way comes" (Act 4, Scene 1). The phrase was also the title of a 1962 novel by Ray Bradbury.