Lex Luthor and Arianna Carlin were married on October 8, 1984.
The title refers to the play "Madame X" by Alexandre Bisson about a lawyer who defends a woman for murder who is his long lost mother. The play had been the basis for eleven movies starting in 1910.
The edition of the Daily Planet that Lois uses to cover the advertisement for Arianna Carlin's column contains the headline "Fruit Fly Spraying." This newspaper was a prop originally created for Pheromone, My Lovely (1993).
This is Denise Crosby's first appearance as Dr. Gretchen Kelly.