There is a flashback of the episode "Let's Call It Quits" (#1.23) that implies that Fred Thompson's character is Edward Wellman Sr., but in the original episode, his name is Keith Faber.
During the bathroom scene, equipment is caught a couple of times moving into and out of view by the mirror Jackie is using.
Throughout the series, Lanford is depicted and described as a small town with a significant blue-collar population, yet the town has an elite country club catered to affluent townspeople.
When Roseanne is sitting on the bathtub in the beginning of the opening scene, a boom mic can be seen in the upper right corner of the screen during the two shot of her and Jackie.