When Captain Janeway and Commander Chakotay say that the Alliance was almost like being part of the Federation again, the original series theme is heard playing in the background.
One of the species pulled into the void (the survey ship) is the Hierarchy that was encountered in the season 6 episode Tinker Tenor Doctor Spy (1999). In that episode they also spied/eavesdropped on other ships.
Jonathan Del Arco (Fantome) played the recurring character Hugh the Borg Drone in Star Trek: The Next Generation (1987) and Star Trek: Picard (2020).
During the musical conversation between Fantome and other members of his species, several musical phrases can be heard from the Star Trek series' opening theme music.
This episode was nominated for an Emmy Award for Outstanding Makeup For A Series.