This is the only mythology episode in the series penned by Vince Gilligan. He largely stuck to stand-alone episodes.
It won an Emmy Award for Outstanding Art Direction for a Series.
The Vegreville snow globe had to be manufactured from scratch to the tune of $2000.
According to Frank Spotnitz, Chris Carter was once in a swimming pool during the holidays when some girl asked him if he was Chris Carter, and then recited to him the beautiful monologue by Scully in the teaser of Memento Mori. He felt very touched.