This was the last Scooby-Doo project created and produced by Joseph Barbera before his death on December 2006.
Casey Kasem was a radio DJ before playing Shaggy in Scooby Doo, Where Are You! (1969). When Shaggy substitutes for Del, he uses Kasem's original manner of orating.
According to the comic book adaptation, Professor Jeffries' first name is Robinson.