This is Shiri Appleby's second time on ER (1994); 14 years ago, she had a small role as a pregnant teenager in the pilot episode.
The title refers to the day ER aired throughout its entire run.
This episode features the last appearance of Dr. Donald Anspaugh, who has been a recurring guest star since season three. Leland Orser, whose first episode was in season eleven, is now the show's senior doctor billed as a special guest star.