When Clair is approaching the diner, some of the patrons switch places from the view outside and when she's inside inside.
The window of the diner says "Breakast Lunch Diner", without an "f" in "Breakfast"
At the start of the episode, as Marie Kramer is staggering down the road, a car approaches and beeps it's horn in annoyance at her as it swerves around her. The car is on the driving on the wrong side of the road, and only goes into the right lane (from it's perspective) when it swerves.
At the beginning of the episode, as Marie Kramer is thrown from the truck, a small square pad can be seen underneath her shirt to soften the blow.
The skyscraper used to establish the teams HQ is the Bank of America building in downtown Miami. The Miami-Dade county courthouse can be seen in the background. There are other establishing shots of this building in prior episodes but do not appear in any episodes following.
In the diner, the officer calls in to dispatch and says he is bringing in a "5150". A "5150" refers to the California code for involuntary commitment. The story takes place in Massachusetts, which would have its own equivalent state law but likely not the same code number.
In the establishing shot of the Patel Health Care building, a Gerber ambulance drives through the shot. Gerber Ambulance is located in Torrance, CA. They do not provide service in Massachusetts where Patel is located.
When discussing the abduction of Emily Kramer, Dr. Bishop refers to intravenous and subcutaneous injection as though they are the same thing; subcutaneous is below the skin, while intravenous means directly into the vein.
When Olivia is telling Clair to come to the door, her Australian accent slips out numerous times. Anna Torv who portrays Olivia is Australian.
When Claire is receiving an injection of red medicine the attendant taps the syringe. This would be done to help remove or dislodge any small or remaining air bubbles from it, but you can clearly see that there is a large airspace in the syringe. One would not tap the syringe until that had been removed. In fact right after that you see that the large air space has been removed even though the attendant never did it.