First appearance of minor character, Scott Malkinson who is constantly mocked for having diabetes and a lisp
In 2010 "The Simpsons" released an episode with the same title; an instance of "South Park" doing something first and having "The Simpsons" copy them.
When asked where the boys have been to be unaware of the High School Musical craze, Craig responds "Peru"; this is a reference to episodes from earlier in season, "Pandemic" and "Pandemic 2: The Startling," in which the boys travel to the country of Peru.
The title is a reference to High School Musical which is parodied in this episode
While the character Bridon is modeled after Zac Efron's character Troy Bolton from High School Musical, the name Bridon sounds similar to the name Dryden, and there's a town in Michigan called Dryden which has a long continuous road which goes to a place called Troy which is south of it.