The film takes place over 6 days, however, Aron's facial hair never increases in length over the course of the movie. No stubble appears and his mustache and chin hair remained the same.
Aron could only manage to get his watch off using his mouth. Then a few scenes later, the watch is back on his wrist.
When Aron is cutting off his arm, his mouth goes from being bloody, to clean, then bloody again.
When Aron's comes out of the mountain, there is blood on his chin and then he takes lot of water, which removes that blood stains but when he starts to walk the blood appears again.
At the beginning of the scene where Aron takes inventory of his supplies after being pinned by the boulder he is hatless. Partway through the scene he inexplicably suddenly has a hat on.
After the boulder initially lands on Aron's arm he decides to remove his backpack to see what he can use to help him get out of this situation. He pulls off the backpack from both shoulders with a fair amount of ease despite his right arm being trapped under a rock and incapacitated. However, although not shown, all he had to do was undo the buckle on the right shoulder strap.
In the initial scene where Aron tries to move the boulder it can be seen to wobble slightly. However, it's described in his book Between a Rock and a Hard Place that when Aron tries to first move the boulder it does wobble slightly, trapping his hand further. He then proceeds to move the boulder back to release the added pressure he caused by moving it.
When Aron rides his bike off the top of his truck, the camera pushes through the back doors of the vehicle. This vehicle appears to be a cargo van (similar to one that crew may use for transport) with doors that open from the center. This cannot be Aron's vehicle as he drives a truck with tailgate and a canopy.
When Aron and the two girls are taking their final photo together, the frame that becomes the photo includes the camera that is supposedly taking the photo.
When Aron is hiking out of the canyon, the actors arm can be briefly seen.
In Aron's guidebook, at the top left of the map, there is an inset with an elevation profile. On the elevation profile, "Aron Ralston's chokestone" is labeled. This label actually appears in current versions of the guidebook.
During the flashback to the game where Aron's girlfriend walks out on him, an ad for the Motorola phone, Droid, can be seen although there was no such thing at the time.
Though the film takes place in 2003, modern-styled (2008) Mountain Dew and Pepsi cans can be seen during Aron's dream sequence when he attends the party.
When Aron takes the Capital One credit card out of his wallet, the logo that is on the card did not come out until 2008.
During the Utah Jazz game, the logo on the court is one that was not used until 2004, when the Jazz changed their color scheme.
During one of the time-lapse sequences of the desert, a person becomes visible for a very short time. They appear in about 5 spots on the screen, only for about one frame.
When Aron is watching the film of Kristi and Megan in the pool on his camera, it moves too far to the left, so a hand is seen pushing the camera back into shot. This can't be Aron's hand as he's holding the camera.
For a brief second, a secondary camera is shown on the right side of the screen as Aron is jumping down to meet the lost women on the trail in the first third of the film.