The last scene ever shot for One Tree Hill was with Brooke and Julian when they are sitting in front of Brooke's childhood home built in Julian's sound stage for his tv show "Ravens".
In the opening scene, James Lafferty's younger brother portrays him in high school, uncredited. Stuart Lafferty also played a family friend in an earlier episode, "I'm Wide Awake, It's Morning" (2.19)
Sophia Bush was the last actor to wrap on the set of One Tree Hill.
In the opening scene where Julian is filming the tv show, Brooke is wearing a necklace shaped like North Carolina, matching Julian's hat with the state on it as well.
This episode is named after a song by U2 and the series title itself.