Last Night Diego helps Dona Teresa get out of jail but for a price. Alfredo makes a sacrifice to save Javier. The family discover Gran Hotel has been made victim of a grave fraud.
A cholera epidemic sweeps through the hotel, threatening the lives of its staff and guests. A dying Diego is going to face his past. Alicia will finally decide if she goes away with Julio or not.
Javier was shot by Adriana's jealous husband. While caring for him, Andrés found his stolen morphine in the nightstand. Belén reveals to Diego that they had twins and threaten him to reveal that she is the real mother of Alejandro.
Belén looks for her missing baby Juan in the village. Meanwhile Alfredo and Sofía baptize their son, unaware that baby Alejandro has a twin, who is in great danger.
Alicia comes face to face with the golden knives killer. Angela's sister comes to ask her for work while Andrés learns the choking truth about his real father. Belén returns with a plan to ruin the Alarcón family.
Julio returns to the hotel to take revenge while trying to persuade Alicia not to marry Diego. Detective Ayala uses fingerprints from the murder weapon to identify the killer and the infamous letter falls into Belén's hands like a godsend.