The title is a play on the classic Nickelodeon show 'You Can't Do That On Television,' which originated the tradition of pouring green slime on the head of anyone who says "I don't know."
Peter's show called Petey's Playhouse is an obvious parody of Pee Wee's Playhouse starring Paul Reubens.
Every episode featuring Mother Maggie is voiced by a high profiled actress:
- In Road to Europe (2002) she is played by Lauren Graham
- In Go, Stewie, Go! (2010) she is played by Anne Hathaway
- In You Can't Do That on Television, Peter (2012) she is played by Katharine McPhee