At the start when Eric hands Calleigh her box she takes it in her right hand. As the shot changes the box is now in her left hand.
Eric Delko refers to the book series as "Love's Last Bite", but at the same time we see a book signing where the series is called "Love's First Bite".
If someone calls in to 911 about a dead body in a house, the first people to arrive would be regular patrol officers not CSI's. In real life, the patrol officers would search the house and after verifying the existence of the dead body would then call in the CSI's.
As Ryan Wolfe is looking at an aerial photo of the island, he comments that it is a "1000 acre island". To be 1000 acres, the round island would need to about 7500 feet across. At that scale, the area of the roof of the house visible on the island would scale out to about 490,000 square feet (over 11 acres under roof), or twice the area of a normal Super Wal-Mart or Home Depot store. The roads on the island scale out to be about 140 feet wide, equal to a 10 lane freeway. The boathouse at the end of the pier would be about 200 feet by 200 feet, 40,000 square feet or about 9/10 of an acre under roof.
Just after Horatio causes the suspect to fall off the tree a red object appears at the lower right corner of the frame. As no other people are there and the are in the woods, it must be some piece of the filming equipment.