Atari was working on a port for their Jaguar CD, but canceled it.
The German localization features the voice of Rolf Schult as the player's briefing officer and narrator in the intro sequence. At the time Creature Shock was released that specific voice had been especially renowned as the German dubbing voice of actor Patrick Stewart in his role as Captain Jean-Luc Picard in the TV series Star Trek: The Next Generation (1987) who in turn sports a similar hairdo like the briefing officer. Though the original multi language UK DOS release features no credits of any particular voice talent.
The movie sequences were all rendered on 486 DX/2 66 [Mhz] workstations, which marked high end computing power at the time of development.
The game's manual had its own ideas of what useful tips can be: "For maximum atmosphere turn down the lights and use headphones instead of speakers."