Actress Kathryn Joosten's character Karen McCluskey was battling lung cancer throughout the series and died from it at the end of this episode. In real life, Kathryn Joosten was also battling lung cancer throughout the series and died from it 20 days after this episode aired. And supposedly, she had the writers incorporate some of her actual health care struggles into some of the struggles of her fictional character.
Carmen, the Solis's new gardener, is a main character in the show's spinoff, Devious Maids.
The most watched series finale in 2012.
Creator Marc Cherry has a brief cameo in this episode. He plays the moving man at Susan's house who is seen carrying a box to the moving truck.
This episode along with episode 22 "Give Me the Blame" aired on the same night. Both episodes serve as the Series Finale.