Rodrigo says that General de Cordoba is awaiting orders from Madrid. Madrid wouldn't be capital of Spain until 1561. In the time-span of the series, the Spanish court was nomadic and the 'capital' would be wherever the monarchs were at the time.
Gacet manipulates the Turks into attacking the Venetians in Cephalonia, triggering the Ottoman-Venetian War of 1499-1503. However, at that time the Turks were already in control of Cephalonia, having taken it from the Kingdom of Naples in 1479. Cephalonia only became Venetian in 1500.