Stewie says to Meg, "Oh my god, we're getting closer to the beginning. You're Lacey Chabert!" This is in reference to Lacey Chabert playing the voice of Meg for the first two seasons of Family Guy before Mila Kunis.
The plot of the film hinges on time moving in reverse. The episode title, "Yug Ylimaf" is the name of the show reversed.
This episode is the 200th episode of Family Guy.
The only episode of the entire series where Lacey Chabert wasn't uncredited.
Road To Germany was infamous for being the first time a character on Family Guy used the word "cunt" (in the uncensored version). In this episode Stewie can be heard saying it again in a deleted scene.