There's a DragonBall gem in this episode when Debbie is helping Lip look for clues of Ian's whereabouts. The top magazine of the stack she picks up resembles the original DragonBall Volume 3 cover. Probably a nod to the actors Justin Chatwin (Jimmy) and Emmy Rossum (Fiona) who played Goku and Bulma in the movie Dragonball Evolution (2009) back in 2009.
The title is taken from the famous "To Be or Not to Be" soliloquy in William Shakespeare's 'Hamlet'.
The scene where Lip is caught by Kenyatta was shot in the Los Angeles City Hall rotunda. The same site was used for the TIAA ad on 'Retire Inequality'.
At the entrance to the building into which Kenyatta chases Lip, it reads "Stephani Feinerman Building". Stephani Feinerman was the set decoration coordinator for several episodes of Shameless.