Yes. Don (Jon Hamm) and Stephanie (Caity Lotz) go on a retreat to the Esalen Institute at Big Sur, California although it is never named. It is, indeed, "up the coast" from Los Angeles as Stephanie describes it, although it is nearer to San Francisco than L.A. Scenes were actually filmed at the institute. It was founded in 1962 and was a popular destination in the 1960s. It is featured in the film
Bob & Carol & Ted & Alice (1969) (1969).