"King of Despair" tries to break down the barrier between the netherworld and Jerusalem's Lot by using Leonardo's "All Seeing Eyes of God". Libra and LHOS work closely together to find Leonardo and Macbeth twins.
In the subway, Leonardo found a person having the wing which shined red. Klaus was surprised to hear it, he call in his mentor; a vampire hunter, Blitz T. Abrams.
The members of Libra are locked out of their headquarters by bizarre insect monsters and must find a way back inside before a catastrophic event devastates the city.
The mixed twins was born in Macbeth family which has PSI; supernatural power. White, the little twin sister can't use her power at all. On the other hand, Black, the elder twin brother has very strong power. The past of twins is revealed in the end.