Though he was mentioned in season 12, this marks the first appearance of the fourth prince of Hell, Asmodeus.
The Panheads Roadhouse neon sign on the wall of the tattoo parlor previously appeared in season 10. In the opening scene of Paper Moon (2014), it is next to the door on the outside of the biker bar.
When Jack is shown watching cartoons, it is a clip from a Scooby-Doo animation, another foreshadowing of Season 13, episode 16.
Drexel says Lucifer will return and 'make Hell great again', a possible reference to the 'Make America Great Again' slogan.
This episode is the premiere of the new character Asmodeus played by Jeffrey Vincent Parisse who played Carlos Rivera on General Hospital. Young John Winchester played by Matt Cohen is currently on General Hospital playing Dr Griffin Munro.