After Carol's patient's transplant surgery is deemed a success, the interns tease her mercilessly about her obvious crush on the surgeon, Dr. Lewis (Patrick Fabian).
Carol pretends to be an attending doctor in order to get her patient into the ICU, and Jenny and Daniel run into Dr. Frost when they finally go on their first date.
Carol excitedly plans an early Christmas celebration for Jenny, but Jenny's preoccupied with her secret first date with Daniel. Also, the doctors investigate a case of food poisoning at an office holiday party.
Lexie and Jenny tease Carol when her kind neighbor shows signs that he has a crush on her. Also, Dr. Frost suggests that Maya and the interns forgo using technology as a crutch and instead use traditional medical procedures on their patients.
When Carol's patient finally makes the liver donation list, she is upset by the lack of emotion from his transplant surgeon, Dr. Lewis (Patrick Fabian). Also, Lexie, Daniel and Caleb try to decipher why Dr. Jacobs has a tattoo of a duck.
Carol has her first "night float", being the only physician on duty for the night. The position comes with enormous pressure, and having already been warned by Dr. Jacobs not to call her, she instead asks Dr. Frost to
As the hospital hosts therapy dogs to help care for their patients, Carol helps Lexie when the emotional burden of being a doctor becomes too "ruff, ".
Carol's dear friend Phyllis (guest star Jane Kaczmarek) is admitted to the hospital, and Carol jealously witnesses what retirement would have looked like for her. Also, Daniel takes credit for Caleb's excellent diagnosis and is bothered when Caleb doesn't seem to mind.