Penelope quotes the song "The End", the love you take is equal to the love you make, by the The Beatles. The episode title is also taken from the song.
Before the show's revival and 16th season in 2022, this episode served as the series finale. It is the 324th episode overall.
As of February 2022, Paramount+ Original Scripted Series President Nicole Clemens said a reboot of the series is "alive and well". Instead of one case per episode, it is rumored to be one case solved over ten episodes. In addition, the streaming service is also working on "The Real Criminal Minds", a documentary series about real FBI profilers.
When Maeve mentions a movie about an angel who gave up his mortality because he fell in love with a human and they spent one day together before she was killed. That movie is City of Angels (1998), with Nicolas Cage and Meg Ryan.