This episode aired on the 60th anniversary of Supergirl's creation, and the 80th anniversary of Batman's creation.
Brenda Strong, who plays Lillian Luthor, is only 5 years older than Jon Cryer, who plays her son Lex Luthor.
When Lena goes to visit her mother in prison, the establishing shot of Albatross Bay is the same establishing shot used for Iron Heights Penitentiary in The Flash (2014).
Although the episode is named after her, Eve is rarely seen in this episode.