I'm not familiar Frank Henenlotter's work. I haven't seen any other of his movies. I watched this one because of the positive comments I found on IMDb. But believe me - watching this movie is complete waste of time. The plot is terrible, the acting is terrible (especially by Charlee Danielson), the special effects are (guess what?) terrible, and the music is simply annoying. The music seems to be made on a cheap keyboard by a person that doesn't know how to make music. It could be a great movie, because the idea for it is good, but there are too many things in it that make it not worth watching. This movie is utterly bad and I don't understand why some people should find it so great.
Review of Bad Biology
