I am not a Jennifer Anniston fan although I have enjoyed the odd thing she has done over the years but she truly is gifted in this portrayal. The movie hinges on this character so if it was not done with great integrity and clarity and humor --it would not work. Ms. Anniston actually looks like a person and not terribly attractive at that --not a movie star in any way. Which is crucial to entering into this story. The supporting characters particularly her "maid" who is absolutely wonderful and integral to the story are mostly well drawn. It is not a movie that to entertain in the light vein (needless to say) but it is well worth watching for this compelling story of a woman in many kinds of pain and how she begins to overcome that overwhelming pain.