The boys take part in a competition to find out who can drink more beer, between Spenny who can hold his alcohol, and Kenny, who is a teetotaler. But, wait. Why is Spenny getting drunker, but Kenny isn't?
The guys take three old ladies out to find out who they like more. Kenny tries to win with his younger brother, Lenny, who has Down Syndrome. Huh? Kenny has a brother named Ronnie, and a sister named Miriam, so who is this guy?
The boys compete before judges in a Comedy Club, Spenny with a stand-up act, and Kenny with a fake TV show, but a letter from the Ministry of Health for Spenny may be the deciding factor.
Kenny uses deception in an attempt to slime as many kisses as humanly possible. Spenny paranoid of catching herpes, uses a direct and honest approach to get women to kiss him.
Kenny and Spenny go back to one of their oldest childhood competitions and decide to race rodents. Will Kenny's rat-like tendencies help him win, or will Spenny's disciplined coaching lead his rat to victory?
Kenny and Spenny square off to see who can sell more bibles. Kenny has a brilliant plan to teach Spenny a moral biblical lesson that he will never forget.
In a total reversal of Kenny's behavior, the guys compete to see who can go longer without being mean to the other. Kenny attempts to overwhelm his best friend with a highly suspicious onslaught of love and caring.
Spenny, who doesn't know much about rap, uses the opportunity to put out an educational message through his music. Kenny uses Spenny's ignorance of rap music against him, rapping his way to the final showdown.