Lucille and Cyril are excited about their wedding but as the day approaches, nothing seems to run smoothly, and the ceremony itself is put in jeopardy.
Demolition work in Poplar uncovers a long-buried secret that leads to a testing and emotional case for the team. Sister Julienne takes on a sensitive delivery.
At the monthly cytology clinic, Sister Frances comforts a young woman who is struggling with a life-changing diagnosis. Lucille supports a difficult mother.
Shelagh organizes a special celebration to mark 100 years since the Order first arrived in Poplar - although Sister Hilda feels that she should have been in charge of the festivities.
Trixie has been assigned to a complicated case involving a crane driver who was injured in a workplace accident and is now paraplegic. Meanwhile, Nancy and Sister Frances give a talk on the facts of life at a primary school.
Sister Monica Joan seeks advice from a clairvoyant. Matthew is shocked to discover squatters in one of his warehouses, and Shelagh faces the most challenging delivery of her career.
An unforeseen event in Poplar means that Nonnatus House suffers its biggest threat yet. But this time it's not the bricks and mortar that are in danger - it's the people.
Nonnatus House faces its darkest day after a tragic incident in the heart of Poplar. As the community rallies together, the team must overcome personal anguish to help the injured.