In the aftermath of the Vas-COM scandal, Goodwin clashes with the hospital's new compliance officer. Crockett and Blake try to save a patient whose son has severe autism. A patient's son lies to his father about his diagnosis.
Crockett and Blake clash with Randall when a famous alcoholic football player needs a liver transplant. Dylan is reluctantly reunited with old friends when their son breaks his arm. Stevie and Charles work together when a patient falls ill after back-alley plastic surgery.
Will and Stevie get stuck in the middle of a marital face-off. Dr. Blake's entire surgical team mysteriously collapses during a liver transplant. Charles encourages Ethan to reconcile with his father.
Dylan and Archer diagnose a pregnant woman with a serious infection. Maggie receives shocking news. Will and Charles question an elderly patient's Alzheimer's diagnosis. In an effort to help, Crockett takes a risk.
Goodwin assigns Med's new compliance officer to a patient with a long-hauler COVID condition. Maggie helps Halstead treat a patient who's been in an iron lung for 60 years.
Dylan's cop instincts come to life when he suspects his patient may be a drug dealer. Charles and Vanessa help a patient who believes she's infested with parasites. Crockett and Blake are paired with an arrogant surgeon.
Will helps a patient with long-haul COVID symptoms. Vanessa reflects on her dating life when she learns that a patient's daughter is having an arranged marriage. A new family is born out of tragedy.
Rival gangs bring their war to Med; Halstead and Charles work with a teenage brain cancer patient who's refusing treatment; tensions run high in the OR when a patient's transplanted uterus fails.
Archer and Asher come into conflict over a patient with close ties to Goodwin. After a patient is shot during a burglary, Scott and Marcel help with the investigation.
Will and Hannah try to save a surrogate's baby; a former patient of Lonnie's goes on a hunger strike; Ethan and Archer help a patient with ties to Ethan's late father; Dylan and Maggie are stumped by a drunk patient who claims to be sober.
Dylan helps the daughter of a mob boss. A grandmother comes to Med desperate to save her grandson. Ethan struggles with some shocking news about his father. Will and Vanessa care for Maggie's high school classmate.
Dylan and Ethan treat a patient shot during a drug raid. Charles and Vanessa work together to properly diagnose a motivational speaker. Will and Hannah must turn to Crockett for help with a patient who's pregnant.
Will and Hannah clash over a patient in need of a kidney transplant. Crockett is faced with a tough decision when Blake is in surgery. Ethan and Archer treat the son of Med's general counsel. Med's family grows.
In the aftermath of Halstead's apartment fire, Marcel, Choi and Archer work together to try and save the survivors. Charles and Med's new fellows, Cuevas, helps a paranoid patient. Scott makes a life-changing decision.
Charles and Cuevas clash over the treatment of a paranoid patient. Choi treats a pregnant woman from Asher's past. Marcel and Taylor help a man who needs a risk neurosurgery.
When a subway train goes off the tracks, Marcel volunteers to help the victims. Taylor and Halstead must decide if they want to risk their jobs to save a patient. Asher and Archer clash over a pregnant patient.
Supply chain shortages continue to impact the ED when Taylor's drug dealer reappears. One of the victims of the recent train crash needs a transplant, forcing Marcel to improvise. Charles and Cuevas help a patient with amnesia.
Marcel adjusts to his newfound fame when he helps Halstead treat a local restaurant owner. Choi, Charles and Goodwin aid a new mother who worries about hurting her baby. Maggie and Taylor clash with a workaholic patient.
Will relies on Crockett and Med's newly donated OR 2.0 to save his patient. Charles helps an elderly confused patient who's mourning the loss of his high school sweetheart.