Sort by Popularity - Most Popular Movies and TV Shows tagged with keyword "fictional-drug"
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1. Dune (2021)
PG-13 | 155 min | Action, Adventure, Drama
A noble family becomes embroiled in a war for control over the galaxy's most valuable asset while its heir becomes troubled by visions of a dark future.
Director: Denis Villeneuve | Stars: Timothée Chalamet, Rebecca Ferguson, Zendaya, Oscar Isaac
Votes: 854,569 | Gross: $108.33M
2. Dune (1984)
PG-13 | 137 min | Action, Adventure, Sci-Fi
A Duke's son leads desert warriors against the galactic emperor and his father's evil nemesis to free their desert world from the emperor's rule.
Director: David Lynch | Stars: Kyle MacLachlan, Virginia Madsen, Francesca Annis, Leonardo Cimino
Votes: 179,407 | Gross: $30.93M
3. Arcane (2021– )
TV-14 | 40 min | Animation, Action, Adventure
Set in Utopian Piltover and the oppressed underground of Zaun, the story follows the origins of two iconic League Of Legends champions and the power that will tear them apart.
Stars: Hailee Steinfeld, Kevin Alejandro, Jason Spisak, Terri Douglas
Votes: 270,234
4. The Matrix (1999)
R | 136 min | Action, Sci-Fi
When a beautiful stranger leads computer hacker Neo to a forbidding underworld, he discovers the shocking truth--the life he knows is the elaborate deception of an evil cyber-intelligence.
Directors: Lana Wachowski, Lilly Wachowski | Stars: Keanu Reeves, Laurence Fishburne, Carrie-Anne Moss, Hugo Weaving
Votes: 2,052,816 | Gross: $171.48M
5. The Batman (2022)
PG-13 | 176 min | Action, Crime, Drama
When a sadistic serial killer begins murdering key political figures in Gotham, Batman is forced to investigate the city's hidden corruption and question his family's involvement.
Director: Matt Reeves | Stars: Robert Pattinson, Zoë Kravitz, Jeffrey Wright, Colin Farrell
Votes: 786,804 | Gross: $369.35M
6. Rise of the Planet of the Apes (2011)
PG-13 | 105 min | Action, Drama, Sci-Fi
A substance designed to help the brain repair itself gives advanced intelligence to a chimpanzee who leads an ape uprising.
Director: Rupert Wyatt | Stars: James Franco, Andy Serkis, Freida Pinto, Karin Konoval
Votes: 558,890 | Gross: $176.76M
7. Star Trek: Deep Space Nine (1993–1999)
TV-PG | 45 min | Action, Adventure, Drama
In the vicinity of the liberated planet of Bajor, the Federation space station Deep Space Nine guards the opening of a stable wormhole to the far side of the galaxy.
Stars: Avery Brooks, Rene Auberjonois, Cirroc Lofton, Alexander Siddig
Votes: 70,774
8. A Clockwork Orange (1971)
R | 136 min | Crime, Sci-Fi
In the future, a sadistic gang leader is imprisoned and volunteers for a conduct-aversion experiment, but it doesn't go as planned.
Director: Stanley Kubrick | Stars: Malcolm McDowell, Patrick Magee, Michael Bates, Warren Clarke
Votes: 881,223 | Gross: $6.21M
9. Dune (2000)
Not Rated | 265 min | Adventure, Drama, Sci-Fi
A three-part miniseries on politics, betrayal, lust, greed and the coming of a Messiah. Based on Frank Herbert's classic science fiction novel.
Stars: William Hurt, Alec Newman, Giancarlo Giannini, Uwe Ochsenknecht
Votes: 24,873
10. Infinity Pool (2023)
R | 117 min | Crime, Horror, Mystery
James and Em Foster are enjoying an all-inclusive beach vacation in the fictional island of La Tolqa, when a fatal accident exposes the resort's perverse subculture of hedonistic tourism, reckless violence and surreal horrors.
Director: Brandon Cronenberg | Stars: Alexander Skarsgård, Mia Goth, Cleopatra Coleman, Dunja Sepcic
Votes: 56,486
11. Children of Men (2006)
R | 109 min | Action, Drama, Sci-Fi
In 2027, in a chaotic world in which women have somehow become infertile, a former activist agrees to help transport a miraculously pregnant woman to a sanctuary at sea.
Director: Alfonso Cuarón | Stars: Julianne Moore, Clive Owen, Chiwetel Ejiofor, Michael Caine
Votes: 529,352 | Gross: $35.55M
12. The Last Airbender (2010)
PG | 103 min | Action, Adventure, Family
Aang, a young successor to a long line of Avatars, must master all four elements and stop the Fire Nation from enslaving the Water Tribes and the Earth Kingdom.
Director: M. Night Shyamalan | Stars: Noah Ringer, Nicola Peltz Beckham, Jackson Rathbone, Dev Patel
Votes: 174,882 | Gross: $131.56M
13. Dredd (2012)
R | 95 min | Action, Crime, Sci-Fi
In a violent, futuristic city where the police have the authority to act as judge, jury and executioner, a cop teams with a trainee to take down a gang that deals the reality-altering drug, SLO-MO.
Director: Pete Travis | Stars: Karl Urban, Olivia Thirlby, Lena Headey, Rachel Wood
Votes: 294,323 | Gross: $13.41M
14. Lucy (I) (2014)
R | 89 min | Action, Sci-Fi, Thriller
A woman, accidentally caught in a dark deal, turns the tables on her captors and transforms into a merciless warrior evolved beyond human logic.
Director: Luc Besson | Stars: Scarlett Johansson, Morgan Freeman, Choi Min-sik, Amr Waked
Votes: 534,236 | Gross: $126.66M
15. 21 Jump Street (2012)
R | 109 min | Action, Comedy, Crime
A pair of underachieving cops are sent back to a local high school to blend in and bring down a synthetic drug ring.
Directors: Phil Lord, Christopher Miller | Stars: Jonah Hill, Channing Tatum, Ice Cube, Brie Larson
Votes: 598,451 | Gross: $138.45M
16. Old (2021)
PG-13 | 108 min | Drama, Horror, Mystery
A vacationing family discovers that the secluded beach where they're relaxing for a few hours is somehow causing them to age rapidly, reducing their entire lives into a single day.
Director: M. Night Shyamalan | Stars: Gael García Bernal, Vicky Krieps, Rufus Sewell, Alex Wolff
Votes: 160,567 | Gross: $48.28M
17. RoboCop (1987)
R | 102 min | Action, Crime, Sci-Fi
In a dystopic and crime-ridden Detroit, a terminally wounded cop returns to the force as a powerful cyborg haunted by submerged memories.
Director: Paul Verhoeven | Stars: Peter Weller, Nancy Allen, Dan O'Herlihy, Ronny Cox
Votes: 283,058 | Gross: $53.42M
18. Code 8 (2019)
Not Rated | 98 min | Action, Crime, Drama
A super-powered construction worker falls in with a group of criminals in order to raise the funds to help his ill mother.
Director: Jeff Chan | Stars: Kari Matchett, Robbie Amell, Penny Eizenga, Lawrence Bayne
Votes: 52,273
19. The Faculty (1998)
R | 104 min | Horror, Mystery, Sci-Fi
When Casey Connor, Herrington High School's newspaper photographer, witnesses the murder of a nurse and sees her alive again, he decides to investigate the bizarre happenings.
Director: Robert Rodriguez | Stars: Jordana Brewster, Clea DuVall, Laura Harris, Josh Hartnett
Votes: 135,080 | Gross: $40.06M
20. Looper (2012)
R | 119 min | Action, Drama, Sci-Fi
In 2074, when the mob wants to get rid of someone, the target is sent into the past, where a hired gun awaits - someone like Joe - who one day learns the mob wants to 'close the loop' by sending back Joe's future self for assassination.
Director: Rian Johnson | Stars: Joseph Gordon-Levitt, Bruce Willis, Emily Blunt, Paul Dano
Votes: 602,928 | Gross: $66.49M
21. Minority Report (2002)
PG-13 | 145 min | Action, Crime, Mystery
John works with the PreCrime police which stop crimes before they take place, with the help of three 'PreCogs' who can foresee crimes. Events ensue when John finds himself framed for a future murder.
Director: Steven Spielberg | Stars: Tom Cruise, Colin Farrell, Samantha Morton, Max von Sydow
Votes: 584,284 | Gross: $132.07M
22. Star Wars: Episode II - Attack of the Clones (2002)
PG | 142 min | Action, Adventure, Fantasy
Ten years after initially meeting, Anakin Skywalker shares a forbidden romance with Padmé Amidala, while Obi-Wan Kenobi discovers a secret clone army crafted for the Jedi.
Director: George Lucas | Stars: Hayden Christensen, Natalie Portman, Ewan McGregor, Christopher Lee
Votes: 758,844 | Gross: $310.68M
23. Limitless (I) (2011)
PG-13 | 105 min | Sci-Fi, Thriller
A mysterious pill that enables the user to access 100% of his brain's abilities transforms a struggling writer into a financial wizard, but it also puts him in a new world with many dangers.
Director: Neil Burger | Stars: Bradley Cooper, Anna Friel, Abbie Cornish, Robert De Niro
Votes: 612,336 | Gross: $79.25M
24. The Fugitive (1993)
PG-13 | 130 min | Action, Crime, Drama
Dr. Richard Kimble, unjustly accused of murdering his wife, must find the real killer while being the target of a nationwide manhunt led by a seasoned U.S. Marshal.
Director: Andrew Davis | Stars: Harrison Ford, Tommy Lee Jones, Sela Ward, Julianne Moore
Votes: 318,619 | Gross: $183.88M
25. Serenity (2005)
PG-13 | 119 min | Action, Adventure, Sci-Fi
The crew of the ship Serenity try to evade an assassin sent to recapture telepath River.
Director: Joss Whedon | Stars: Nathan Fillion, Gina Torres, Chiwetel Ejiofor, Alan Tudyk
Votes: 305,656 | Gross: $25.51M
26. Planet Terror (2007)
R | 105 min | Action, Comedy, Horror
After an experimental bio-weapon is released, turning thousands into zombie-like creatures, it's up to a rag-tag group of survivors to stop the infected and those behind its release.
Director: Robert Rodriguez | Stars: Rose McGowan, Freddy Rodríguez, Josh Brolin, Marley Shelton
Votes: 223,240
27. Freddy vs. Jason (2003)
R | 97 min | Action, Horror
Freddy Krueger and Jason Voorhees return to terrorize the teenagers of Elm Street. Only this time, they're out to get each other, too.
Director: Ronny Yu | Stars: Robert Englund, Ken Kirzinger, Kelly Rowland, Monica Keena
Votes: 127,265 | Gross: $82.62M
28. The Hitchhiker's Guide to the Galaxy (2005)
PG | 109 min | Adventure, Comedy, Sci-Fi
Mere seconds before the Earth is to be demolished by an alien construction crew, journeyman Arthur Dent is swept off the planet by his friend Ford Prefect, a researcher penning a new edition of "The Hitchhiker's Guide to the Galaxy."
Director: Garth Jennings | Stars: Martin Freeman, Yasiin Bey, Sam Rockwell, Zooey Deschanel
Votes: 208,376 | Gross: $51.09M
29. Equilibrium (2002)
R | 107 min | Action, Drama, Sci-Fi
In an oppressive future where all forms of feeling are illegal, a man in charge of enforcing the law rises to overthrow the system and state.
Director: Kurt Wimmer | Stars: Christian Bale, Sean Bean, Emily Watson, Taye Diggs
Votes: 346,997 | Gross: $1.20M
30. A Nightmare on Elm Street 3: Dream Warriors (1987)
R | 96 min | Fantasy, Horror
A psychiatrist familiar with knife-wielding dream demon Freddy Krueger helps teens at a mental hospital battle the killer who is invading their dreams.
Director: Chuck Russell | Stars: Heather Langenkamp, Robert Englund, Craig Wasson, Patricia Arquette
Votes: 90,290 | Gross: $44.79M
31. Star Trek II: The Wrath of Khan (1982)
PG | 113 min | Action, Adventure, Sci-Fi
With the assistance of the Enterprise crew, Admiral Kirk must stop an old nemesis, Khan Noonien Singh, from using the life-generating Genesis Device as the ultimate weapon.
Director: Nicholas Meyer | Stars: William Shatner, Leonard Nimoy, DeForest Kelley, James Doohan
Votes: 129,201 | Gross: $78.91M
32. Limitless (2015–2016)
TV-14 | 42 min | Comedy, Crime, Drama
An average 28-year-old man who gains the ability to use the full extent of his brain's capabilities is hired by the F.B.I. as a consultant.
Stars: Jake McDorman, Jennifer Carpenter, Hill Harper, Mary Elizabeth Mastrantonio
Votes: 71,914
33. Videodrome (1983)
R | 87 min | Horror, Sci-Fi, Thriller
A programmer at a Toronto TV station that specializes in adult entertainment searches for the producers of a dangerous and bizarre broadcast.
Director: David Cronenberg | Stars: James Woods, Debbie Harry, Sonja Smits, Peter Dvorsky
Votes: 102,967 | Gross: $2.12M
34. Spiderhead (2022)
R | 106 min | Action, Crime, Drama
In the near future, convicts are offered the chance to volunteer as medical subjects to shorten their sentence. One such subject for a new drug capable of generating feelings of love begins questioning the reality of his emotions.
Director: Joseph Kosinski | Stars: Chris Hemsworth, Miles Teller, Jurnee Smollett, Mark Paguio
Votes: 66,403
35. RoboCop 2 (1990)
R | 117 min | Action, Crime, Sci-Fi
RoboCop returns to protect the citizens of old Detroit but faces a deadly challenge when a rogue OCP member secretly creates a new, evil RoboCop 2.
Director: Irvin Kershner | Stars: Peter Weller, Nancy Allen, Belinda Bauer, Dan O'Herlihy
Votes: 93,156 | Gross: $45.68M
36. Strange Days (1995)
R | 145 min | Crime, Drama, Sci-Fi
A former cop turned street-hustler accidentally uncovers a conspiracy in Los Angeles in 1999.
Director: Kathryn Bigelow | Stars: Ralph Fiennes, Angela Bassett, Juliette Lewis, Tom Sizemore
Votes: 78,424 | Gross: $7.92M
37. Firestarter (2022)
R | 94 min | Drama, Horror, Sci-Fi
A young girl tries to understand how she mysteriously gained the power to set things on fire with her mind.
Director: Keith Thomas | Stars: Zac Efron, Ryan Kiera Armstrong, Sydney Lemmon, Michael Greyeyes
Votes: 22,098
38. 3 Days to Kill (2014)
PG-13 | 117 min | Action, Drama, Thriller
A dying CIA agent trying to reconnect with his estranged daughter is offered an experimental drug that could save his life in exchange for one last assignment.
Director: McG | Stars: Kevin Costner, Hailee Steinfeld, Connie Nielsen, Amber Heard
Votes: 97,634 | Gross: $30.70M
39. Heavy Metal (1981)
R | 86 min | Animation, Adventure, Fantasy
A glowing green orb that embodies ultimate evil terrorizes a young girl with an anthology of bizarre and fantastic stories.
Directors: Gerald Potterton, John Bruno, John Halas, Julian Harris, Jimmy T. Murakami, Barrie Nelson, Paul Sabella, Jack Stokes, Pino Van Lamsweerde, Harold Whitaker | Stars: Richard Romanus, John Candy, Joe Flaherty, Don Francks
Votes: 38,152
40. Brave New World (2020)
TV-MA | 418 min | Drama, Sci-Fi, Thriller
In a utopia whose perfection hinges upon control of monogamy and privacy, members of the collective begin to question the rules, putting their regimented society on a collision course with forbidden love and revolution.
Stars: Alden Ehrenreich, Jessica Brown Findlay, Harry Lloyd, Nina Sosanya
Votes: 17,040
41. Grosse Pointe Blank (1997)
R | 107 min | Action, Comedy, Crime
Martin Blank is a professional assassin. He is sent on a mission to a small Detroit suburb, Grosse Pointe, and, by coincidence, his ten-year high school reunion party is taking place there at the same time.
Director: George Armitage | Stars: John Cusack, Minnie Driver, Dan Aykroyd, Joan Cusack
Votes: 99,613 | Gross: $28.01M
42. Repo! The Genetic Opera (2008)
R | 98 min | Horror, Musical, Sci-Fi
A worldwide epidemic encourages a biotech company to launch an organ-financing program similar in nature to a standard car loan. The repossession clause is a killer, however.
Director: Darren Lynn Bousman | Stars: Paul Sorvino, Anthony Head, Alexa PenaVega, Sarah Brightman
Votes: 26,539 | Gross: $0.14M
43. A Scanner Darkly (2006)
R | 100 min | Animation, Comedy, Crime
An undercover cop in a not-too-distant future becomes involved with a dangerous new drug and begins to lose his own identity as a result.
Director: Richard Linklater | Stars: Keanu Reeves, Winona Ryder, Robert Downey Jr., Rory Cochrane
Votes: 117,120 | Gross: $5.50M
44. Side Effects (I) (2013)
R | 106 min | Crime, Drama, Mystery
A young woman's world unravels when a drug prescribed by her psychiatrist has unexpected side effects.
Director: Steven Soderbergh | Stars: Rooney Mara, Channing Tatum, Jude Law, Catherine Zeta-Jones
Votes: 197,125 | Gross: $32.17M
45. Scanners (1981)
R | 103 min | Horror, Sci-Fi, Thriller
A scientist trains a man with an advanced telepathic ability called "scanning" to stop a dangerous Scanner with extraordinary psychic powers from waging war against non scanners.
Director: David Cronenberg | Stars: Jennifer O'Neill, Stephen Lack, Patrick McGoohan, Lawrence Dane
Votes: 61,745 | Gross: $14.23M
46. Derailed (I) (2005)
R | 108 min | Crime, Drama, Thriller
When two married business executives having an affair are blackmailed by a violent criminal, the two must turn the tables on him to save their families.
Director: Mikael Håfström | Stars: Clive Owen, Jennifer Aniston, Vincent Cassel, Addison Timlin
Votes: 76,378 | Gross: $36.02M
47. Naked Lunch (1991)
R | 115 min | Drama, Mystery
After developing an addiction to the substance he uses to kill bugs, an exterminator accidentally kills his wife and becomes involved in a secret government plot being orchestrated by giant bugs in a port town in North Africa.
Director: David Cronenberg | Stars: Peter Weller, Judy Davis, Ian Holm, Julian Sands
Votes: 56,646 | Gross: $2.54M
48. Osmosis Jones (2001)
PG | 95 min | Animation, Action, Adventure
A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.
Directors: Bobby Farrelly, Peter Farrelly | Stars: Laurence Fishburne, Chris Rock, David Hyde Pierce, Brandy Norwood
Votes: 38,758 | Gross: $13.60M
49. Junior (1994)
PG-13 | 109 min | Comedy, Romance, Sci-Fi
As part of a fertility research project, a male scientist agrees to carry a pregnancy in his own body.
Director: Ivan Reitman | Stars: Arnold Schwarzenegger, Danny DeVito, Emma Thompson, Frank Langella
Votes: 72,987 | Gross: $36.76M
50. Max Payne (2008)
PG-13 | 100 min | Action, Crime, Drama
Coming together to solve a series of murders in New York City are a police detective and an assassin, who will be hunted by the police, the mob, and a ruthless corporation.
Director: John Moore | Stars: Mark Wahlberg, Mila Kunis, Beau Bridges, Ludacris
Votes: 130,173 | Gross: $40.69M